The premise is really simple: each time the fantastic hosts Tim and Giannis invite one senior academic to discuss their favourite publication from the recent literature.
Pour yourself a nice glass of wine and join us as we delve into recent literature, and perhaps learn a little from the minds that have shaped the field.
We’ll find out what caught their eye, and why it is worth taking a closer look at this particular publication. Along the way, we will learn about their publication strategies and possibly even glimpse into the future of this amazing field of research.
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Latest Edition
Edition #6: Elisabeth de Vries, Groningen
In this episode we talk about nectin-4 – an emerging biomarker for cancer diagnosis and therapy – with one of the most influential and distinguished scientists in medical oncology, Elisabeth de Vries.
We talk about the first-in-human study of a radioligand that can target nectin-4 and learn what medical oncologists need to get out from imaging data so that these powerful tools continue to make an impact on optimized patient treatment.
We learn about the importance and best practices of solid clinical trials, but also about the hurdles and difficulties in design (and finance) these.
Along the way, we get a glimpse into Elisabeth’s career path and her future research plans with a very clear focus to further improve patient diagnosis and treatment.
Selected publication:
First-in-human study of the radioligand 68Ga-N188 targeting nectin-4 for PET/CT imaging of advanced urothelial carcinoma.
X. Duan, L. Xia, Z. Zhang, Y. Ren, M. G. Pomper, S. P. Rowe, X. Li, N. Li, N. Zhang, H. Zhu 6, Z. Yang, X. Sheng, X. Yang. Clin Cancer Res. 2023 Apr 24; CCR-23-0609. doi: 10.1158/1078-0432.CCR-23-0609.
About the Guest
Elisabeth is a world-renowned Professor of Medical Oncology at the University Medical Centre Groningen. She is involved in patient care, teaching and research. Her research lines aim to increase the sensitivity of tumours to anticancer drugs, and she uses imaging techniques to support this.
She actively promotes a multidisciplinary approach with close interactions between the laboratories and clinic as crucial prerequisite to improve prospects for cancer patients.
She received numerous awards and grants and is a member of the Royal Academy of Arts and Sciences (KNAW), Fellow of the European Academy of Cancer Sciences, and (co)-authored >840 publications (H-index: 137).
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About the Hosts
Tim Witney is a Wellcome Trust Senior Research Fellow and Reader in Molecular Imaging at King’s College London’s School of Biomedical Engineering & Imaging Sciences. His Group’s research focuses on the development of next-generation imaging tools for cancer diagnosis, monitoring of therapeutic response, and detection of drug resistance. Tim has been serving as member of the ESMI Board since 2018.
Giannis Zacharakis is a Principal Researcher at the Institute of Electronic Structure and Laser – Foundation for Research and Technology (FORTH – IESL) in Heraklion, Crete and the Head of the Laboratory for Biophotonics and Molecular Imaging. Giannis was elected as ESMI Vice President in 2018 and served as President from 2019 to 2020.
About the music
- Andreas Jacobs – violin
- Jacob Niller – accordion
- Wolfgang Platen – contrabass
All of you who attended the EMIM 2021 in Göttingen certainly remember Andreas – one of the society’s founding fathers and past presidents – on stage playing the violin. Together with two young, talented musicians, he recorded Olecht Konflytt* again for the special occassion of becoming the “Dive into Imaging Science” theme – we could not be more grateful!
*composer: Guido Jäger “Olecht Konflytt”
LATEST Edition | 06/2023
Guest:
Elisabeth de Vries, Groningen
First-in-human study of the radioligand 68Ga-N188 targeting nectin-4 for PET/CT imaging of advanced urothelial carcinoma.
X. Duan, L. Xia, Z. Zhang, Y. Ren, M. G. Pomper, S. P. Rowe, X. Li, N. Li, N. Zhang, H. Zhu 6, Z. Yang, X. Sheng, X. Yang. Clin Cancer Res. 2023 Apr 24; CCR-23-0609. doi: 10.1158/1078-0432.CCR-23-0609.