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The premise is really simple: each episode the fantastic hosts Tim and Giannis invite one senior academic guest to discuss their favourite publication from the recent literature.

Pour yourself a nice glass of wine (we always record late in the evening) and join us as we delve into recent literature, and perhaps learn a little from the minds that have shaped the field.

We’ll find out what caught their eye, and why it is worth taking a closer look at this particular publication. Along the way, we will learn about their publication strategies and possibly even glimpse into the future of this amazing field of research.

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CHRISTMAS Edition 12/2024

Episode #13: Fabian Kiessling, Aachen

Welcome to the Christmas edition of “Dive into imaging science”! Giannis and Tim have their festive hats on and are wearing their dodgy Christmas jumpers, ready for a cracker (!) of an episode. And we have a very special guest on the show – none other than our current past president, Fabian Kiessling, who heads up the Institute of Experimental Molecular Imaging and the Helmholtz Institute for Biomedical Engineering at Aachen University.  

We explore how to ‘make the visible invisible’ in the groundbreaking paper from the lab of Guosong Hong at Stanford by achieving optical transparency in live animals using a food dye that’s an ingredient in many potato chips! We conclude that this isn’t, in fact, the end of non-invasive imaging; instead, it opens a new frontier for optical and photoacoustic techniques.  

Along the way, we learn that Fabian could have been a policeman if only he hadn’t been “a little bit weak in differentiating red and green” and that being a scientist is very much like being an artist. We discuss reproducibility in science, the importance of co-locating labs and people, and were swept along by Fabian’s passion for imaging science. 

 Continuing our tradition, we enjoy a special cocktail :
It’s a Christmas and Aachen special so what better way to celebrate it with a twist on the Gluehwein Cretan style: Giannis’ own home-made brandy and raki (cretan grappa that is), red wine, cinnamon sticks, cloves, honey and a red orange slice from his garden.

Selected publication:

Achieving optical transparency in live animals with absorbing molecules

Ou Z, Duh YS, Rommelfanger NJ, Keck CHC, Jiang S, Brinson K Jr, Zhao S, Schmidt EL, Wu X, Yang F, Cai B, Cui H, Qi W, Wu S, Tantry A, Roth R, Ding J, Chen X, Kaltschmidt JA, Brongersma ML, Hong G. Achieving optical transparency in live animals with absorbing molecules. Science. 2024 Sep 6;385(6713):eadm6869. doi: 10.1126/science.adm6869. Epub 2024 Sep 6. PMID: 39236186.

About the Guest

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About the Hosts

Tim Witney is a Wellcome Trust Senior Research Fellow and Reader in Molecular Imaging at King’s College London’s School of Biomedical Engineering & Imaging Sciences. His Group’s research focuses on the development of next-generation imaging tools for cancer diagnosis, monitoring of therapeutic response, and detection of drug resistance. Tim has been serving as member of the ESMI Board since 2018, and became Secretary in 2023.

Giannis Zacharakis is a Principal Researcher at the Institute of Electronic Structure and Laser – Foundation for Research and Technology (FORTH – IESL) in Heraklion, Crete and the Head of the Laboratory for Biophotonics and Molecular Imaging. Giannis was elected as ESMI Vice President in 2018 and served as President from 2019 to 2020.

Tim Witney, London & Giannis Zacharakis, Heraklion

About the music

  • Andreas Jacobs – violin
  • Jacob Niller – accordion
  • Wolfgang Platen – contrabass

All of you who attended the EMIM 2021 in Göttingen certainly remember Andreas – one of the society’s founding fathers and past presidents – on stage playing the violin. Together with two young, talented musicians, he recorded Olecht Konflytt* again for the special occassion of becoming the “Dive into Imaging Science” theme – we could not be more grateful!

*composer: Guido Jäger “Olecht Konflytt”

LATEST Edition | 10/2024

Guest: Elisa E. Konofagou, New York

Features Paper: Transthoracic ultrasound localization microscopy of myocardial vasculature in patients

Yan J, Huang B, Tonko J, Toulemonde M, Hansen-Shearer J, Tan Q, Riemer K, Ntagiantas K, Chowdhury RA, Lambiase PD, Senior R, Tang MX. Transthoracic ultrasound localization microscopy of myocardial vasculature in patients. Nat Biomed Eng. 2024 Jun;8(6):689-700. doi: 10.1038/s41551-024-01206-6. Epub 2024 May 6. PMID: 38710839; PMCID: PMC11250254.

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All Guests & Editions

  • #13: Fabian Kiessling, Aachen
  • #12: Elisa Konofagou, New York
  • #11: John Ronald, London ON
  • #10: Kevin Brindle, Cambridge
  • #9: Mikhail Shapiro, Pasadena
  • #8: Jason Lewis, New York
  • #7: Annemie Van Der Linden, Antwerp
  • #6: Elisabeth de Vries, Groningen
  • #5: Bernd Pichler, Tübingen
  • #4: Zaver Bhujwalla, Baltimore
  • #3: Clemens WGM Lowik, Rotterdam
  • #2 Simon Cherry, UC Davis
  • #1 Jolanda de Vries, Nijmegen
  • #0: Bertrand Tavitian, Paris