Recording webinar 
Heart & Lung in Focus: Advances in Cardiopulmonary Imaging | Edition #1
Date:
Jun 18, 2025
Speaker 1:
Kaye Morgan, Melbourne
Title: “Novel approaches to x-ray phase and dark-field imaging of the lung”
Speaker 2:
Oscar Van Der Have, Lund
Title: “Synchrotron-based Micro-CT for Translational Research on the Pulmonary Circulation”
Speaker 3:
Frances de Man, Amsterdam
Title: “Unlocking the chamber of secrets: Right heart failure in Pulmonary Hypertension”
Chairs:
Alkystis Phinikaridou, London & Bram Coolen, Amsterdam (CARDIO group)
Emmanuel Brun, Grenoble & Irma Mahmutovic-Persson, Lund (X-Ray/Lung group)
About the Speakers
Kaye Morgan, Melbourne
Prof Kaye Morgan works in x-ray imaging in the School of Physics and Astronomy in the Faculty of Science at Monash University. Her research program is focused on developing and applying innovative methods of x-ray imaging that capture phase and dark-field information. She is most well-known as the lead author of the first papers describing a new approach to phase/dark-field x-ray imaging, known as speckle-based and single-grid imaging. She is working both on developing and extending these methods and on applying them to medical research questions.
Oscar Van Der Have, Lund
Dr. Oscar van der Have is a physician in pediatric cardiology at Skåne University Hospital in Lund, Sweden. He holds a medical degree from Lund University, where he also completed a PhD in experimental vascular biology. His doctoral research focused on pulmonary vasculopathy, employing advanced three-dimensional synchrotron-based imaging to investigate the role of extracellular matrix proteoglycans in pulmonary arterial hypertension. Currently undergoing residency training, Oscar is committed to a career as a clinician-scientist. He plans to integrate his clinical and research interest, to better understand the role of the extracellular matrix in cardiac development and heart failure.
Frances de Man, Amsterdam
Prof. Frances de Man is director of the translational PHEniX laboratory and embedded in the Department of Pulmonary Medicine at Amsterdam UMC and Amsterdam Cardiovascular Sciences research institute. With a background in Biomedical Sciences and a postdoctoral degree in Epidemiology, her research focuses on right heart failure in pulmonary arterial hypertension. Following her PhD at VU University Medical Center, she completed an ERS/Marie Curie-funded postdoctoral fellowship in Paris, investigating endothelial–smooth muscle cell interactions in the pulmonary vasculature. Her work integrates in vivo, ex vivo, and in vitro models – including patient-derived cardiomyocytes – to uncover mechanisms of right ventricular adaptation and identify novel therapeutic targets. Her ultimate goal is to improve outcomes for patients with PAH by preventing the progression to right heart failure. Frances has been awarded multiple prestigious grants and leads several national and international consortia.
Importance & Purpose
Non-invasive in vivo imaging plays a pivotal role in the characterization of cardiovascular diseases in small animal models and in the evaluation of the efficacy of new treatments. Echography and MRI allow for precise analysis of the morphology and the function of the heart and the precise characterization of the structure of the vessel wall. Molecular imaging using radioactive or optical probes offers to identify with high sensitivity biological processes taking place inside cardiovascular tissues. Each of these imaging techniques provides complementary information on cardiovascular diseases and is subjected to similar constraints in relation to cardiac and respiratory motion.
The aim of this study group will be to tighten interactions between the research groups working on each imaging modality and stimulate the development of multi-modality imaging projects in the cardiovascular field.
Objectives
- To foster new and integrated approaches in pre-clinical cardiovascular imaging.
- To disseminate the applications of imaging to basic researchers working in cardiovascular research and to support clinical translation of new technologies.
- To support cooperative strategies in cardiovascular imaging and develop dedicated networks.
- To organize state-of-the-art sessions not only at ESMI meetings, but also at relevant other meetings
- To identify current educational workshops and identify the demand for organizing hands-on workshops
Group Review Article
Current and Emerging Preclinical Approaches for Imaging-based Characterization of Atherosclerosis
Vigne, J., Thackeray, J., Essers, J., Makowski, M., Varasteh, Z., Baleanu-Curaj, A., Karlas, A., Canet-Soulas, E., Mulder, W., Kießling, F., Schäfers, M., Botnar, R., Wildgruber, M., Hyafil, F.
Founding Members
- René Botnar, London
- Emmanuelle Canet-Soulas, Lyon
- Jeroen Essers, Rotterdam
- Fabien Hyafil, Paris
- Marcus Makowski, Berlin
- Willem Mulder, Eindhoven
- Alkystis Phinikaridou, London
- Jeanine Prompers, Utrecht
- Christoph Rischpler, Munich
- Antti Sarraste, Turku
- Michaee Schäfers, Münster
- James Thackeray, Hannover
- Moritz Wildgruber, Munich
Group Leadership
- Chair: Alkystis Phinikaridou, London
- Co-Chair: Bram Coolen, Amsterdam
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